ACE INHIBITORS

By -
ACE means Angiotensin-Converting Enzyme , so now we are going to talk about Angiotensin-converting enzyme (ACE) inhibitors , it helps to release your veins and arteries to lower your blood pressure . ACE inhibitors prevent an enzyme in your body from producing angiotensin II, a substance that narrows your blood vessels. This narrowing can cause high blood pressure and force your heart to work harder.
What is the function of ACE

Angiotensin-converting enzyme or ACE, is a central component of the renin–angiotensin system (RAS), which controls blood pressure by regulating the volume of fluids in the body. It converts the hormone angiotensin I to the active vasoconstrictor angiotensin II.

What are the drugs of ACE Inhibitors
  • Benazepril (Lotensin)
  • Captopril.
  • Enalapril (Vasotec)
  • Fosinopril.
  • Lisinopril (Prinivil, Zestril)
  • Moexipril.
  • Perindopril.
  • Quinapril (Accupril)

What is the mechanism of action of ACE Inhibitors

ACE inhibitors work by interfering with the body's renin-angiotensin-aldosterone system , it can shortly called as RAAS ,  renin-angiotensin-aldosterone system is a complex system responsible for regulating the body's blood pressure. The kidneys release an enzyme called renin in response to low blood volume, low sodium ( salt ) levels or high potassium levels.

Will ACE Inhibitors increase or decrease cardiac output .

ACE inhibitors decrease systemic vascular resistance but cause little change in heart rate. In normotensive and hypertensive subjects with normal left ventricular function , ACE inhibitors have little effect on cardiac output or pulmonary capillary wedge pressure.

What are the contraindications for ACE inhibitors

Contraindications to ACE Inhibitor use include hyperkalemia ,  renal artery stenosis, pregnancy (ACE Inhibitor or Australian Drug Evaluation Committee [ADEC] pregnancy category D) , or prior adverse reaction to an ACE Inhibitor including angioedema .

Who should not take ACE inhibitors

  • Pregnant women.
  • People with severe kidney failure.
  • People who have ever had a severe allergic reaction that caused their tongue and lips to swell, even if it was from a bee sting , should not take ACE inhibitors

What's the difference between a beta blocker and an ACE inhibitor

Beta-blockers treat many of the same conditions as ACE inhibitors , including high blood pressure , chronic heart failure, and stroke. Both types of medications also prevent migraines. Unlike ACE inhibitors, however, beta-blockers can help relieve angina (chest pain)




Comments

Post a Comment

Popular posts from this blog

Penicillin

By -
Image
 Penicillin is a type of antibiotic that was discovered in 1928 by Alexander Fleming. It is used to treat a variety of bacterial infections, including streptococcal infections, pneumonia, meningitis, and others. Penicillin works by interfering with the bacteria's cell wall formation, causing the bacteria to eventually lyse (burst) and die. Penicillin is considered one of the first "miracle drugs" and revolutionized the treatment of bacterial infections. However, over time, some bacteria have developed resistance to penicillin, and as a result, other antibiotics have been developed to treat these resistant strain. usages of penicillin Penicillin is commonly used to treat a variety of bacterial infections, including: Strep throat and other streptococcal infections Pneumonia Meningitis Otitis media (ear infections) Skin and soft tissue infections Urinary tract infections Gastrointestinal infections Endocarditis (infection of the inner lining of the heart) It is important to ...
Read more

Cholesterol

By -
Image
 Do you have cholesterol ?  let’s talk about you , Where does cholesterol comes from,                The cholesterol in your blood comes from the two sources those are the foods you eat and your liver ,             Your liver makes all the cholesterol your body needs , cholesterol and other fats are carried inyour blood stream as spherical particles called lipoproteins . How to avoid cholesterol from your body         1.    Reduce    saturated fats , saturated fats , found primarily in red meat and full fat dairy products   raise your total cholesterol . 2.    Eliminate trans fats 3.    Eat foods rich in omega – 3 fatty acids 4.    Increase soluble fiber 5. Add whey protein  What are the foods you should take for cholesterol   Focus on fruits, vegetables, whole grains, and beans. Be mindful of...
Read more

PARACETAMOL

By -
Image
  Paracetamol, also known as acetaminophen, is a widely used over-the-counter medication commonly used to relieve pain and reduce fever. It is a non-opioid analgesic and antipyretic drug. Paracetamol works by inhibiting the production of certain chemicals in the body that cause pain and fever. Here are some key points about paracetamol: Uses: Paracetamol is primarily used to relieve mild to moderate pain associated with conditions such as headaches, toothaches, menstrual cramps, muscle aches, and osteoarthritis. It is also used to reduce fever caused by various illnesses. Dosage: The appropriate dosage of paracetamol depends on several factors, including the age and weight of the individual. It is important to follow the instructions on the packaging or consult a healthcare professional for the correct dosage. Safety: Paracetamol is generally considered safe when used as directed. However, it can be harmful if taken in excessive amounts. Overdosing on paracetamol can cause liver da...
Read more