METHIMAZOLE
Methimazole is usually preferred over
propylthiouracil because it reverses hyperthyroidism more quickly and has fewer side
effects. Methimazole requires
an average of six weeks to lower T4 levels to normal and is often given before
radioactive iodine treatment. Methimazole can
be taken once per day. Methimazole is used to treat hyperthyroidism, a condition that
occurs when the thyroid gland produces too much thyroid hormone. It is also
taken before thyroid surgery or
radioactive iodine therapy. This medication is
sometimes prescribed for other uses , ask your doctor or pharmacist for more
information.
What does Methimazole do to cells
Methimazole prevents
iodine and peroxidase from their normal interactions with thyroglobulin to form
T4 and T3. This action decreases thyroid hormone production. Methimazole also interferes with
the conversion of T4 to T3. Since T3 is more potent than T4, this also reduces
the activity of thyroid hormones.
Will Methimazolehelp me lose weight
After methimazole treatment,
body weight was
initially increased (0–8 weeks), subsequently plateaued ( 8 – 24 weeks) , and
gradually decreased in the later period ( 24–52 weeks ) despite the decreased
food intake.
What are the side effects of taking Methimazole
- Nausea , vomiting , upset stomach
- headache , dizziness , drowsiness
- numbness or tingly feeling
- rash , itching ,
skin discoloration
- muscle or joint pain
- hair loss
- decreased sense of taste
What is the best time of day to take Methimazole
Food in your stomach may change the amount of methimazole that is able to enter the bloodstream. To make sure that you always get the same effects, try to take methimazole at the same time in relation to meals every day. That is, always take it with meals or always take it on an empty stomach.
How does methimazole make you feel
numbness or tingly feeling – rash , itching , skin discoloration , muscle or joint
pain , hair loss.
What happens if Methimazoleis high
Overdose symptoms may include nausea , vomiting , upset
stomach , headache , joint pain , fever
, itching , swelling , or pale skin and easy bruising or bleeding.
Can Methimazole cause problems
swollen glands in your neck or jaw or liver problems – nausea , upper stomach pain
, itching , tiredness , loss of appetite , dark urine , clay - colored stools ,
jaundice ( yellowing of the skin or eyes ) .
Methimazole available strength
Adult. The initial daily dosage is 15 mg for mild hyperthyroidism ,
30 to 40 mg for
moderately severe hyperthyroidism, and 60 mg for severe hyperthyroidism , divided into 3 doses at 8 hour
intervals. The maintenance dosage is 5 to 15 mg daily.
What type of drug is Methimazole
Methimazole is
a thionamide antithyroid agent that inhibits the synthesis of thyroid hormones.
Can Methimazole cause liver damage
A frequent treatment for hyperthyroidism is antithyroid
medications, either Methimazole or
Propylthiouracil. It is known that both medications, as well as hyperthyroidism
itself, can affect the
function of the liver, causing increases in blood levels
of markers of liver function
know as liver function
tests.
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