Ofloxacin

 


What drug class is Ofloxacin

Ofloxacin may also be used to treat bronchitis and urinary tract infections but should not be used for bronchitis and some types of urinary tract infections if other treatments are available. Ofloxacin is in a class of antibiotics called fluoroquinolones . It works by killing bacteria that cause infections.

What is Ofloxacin used for

Ofloxacin is used to treat certain infections including pneumonia, and infections of the skin, bladder, reproductive organs, and prostate (a male reproductive gland).

When should I take Ofloxacin

It is usually taken with or without food twice a day for 3 days to 6 weeks. The length of treatment depends on the type of infection being treated. Your doctor will tell you how long to take ofloxacin. Take ofloxacin at around the same times every day and try to space your doses 12 hours apart.

What is the action of Ofloxacin

Ofloxacin is a quinolone antimicrobial agent. The mechanism of action of ofloxacin and other fluoroquinolone antimicrobials involves inhibition of bacterial topoisomerase IV and DNA gyrase (both of which are type II topoisomerases), enzymes required for DNA replication , transcription , repair and recombination.


What are the side effects of Ofloxacin

  • nausea.
  • diarrhea.
  • constipation.
  • gas.
  • vomiting.
  • stomach pain or cramps.
  • change in ability to taste food.
  • loss of appetite.

What is the meaning of Ofloxacin

Ofloxacin is a fluoroquinolone antibiotic that fights bacteria in the body. Ofloxacin is used to treat bacterial infections of the skin, lungs, prostate, or urinary tract (bladder and kidneys). Ofloxacin is also used to treat pelvic inflammatory disease and Chlamydia and / or gonorrhea.

What is the indication of Ofloxacin

Indications

Single and Daily Doses

Gonococcal urethritis and cervicitis due to susceptible Neisseria gonorrhoeae

400 mg

Uncomplicated cystitis

200 mg-400 mg daily

Acute pyelonephritis and complicated urinary tract infections

400 mg daily, increasing if necessary, to 400 mg twice a day

Community-acquired pneumonia.

Acute exacerbations of chronic obstructive pulmonary disease including bronchitis.

400 mg daily, increasing, if necessary, to 400 mg twice a day

Non-gonococcal urethritis and cervicitis

400 mg daily


what is the contraindication of
Ofloxacin

diarrhea from an infection with Clostridium difficile bacteria. diabetes. low blood sugar. dehydration.




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